Anti-Cadherin-16 (M810) Antibody

Cadherin-16, also termed kidney-specific (Ksp) cadherin, is a tissue-restricted cadherin family member expressed chiefly in renal tubular epithelium, where it helps maintain epithelial polarity and junctional integrity. Antibodies.com offers this rabbit polyclonal reagent as an unconjugated primary antibody for researchers investigating nephrogenesis, tubular transport biology, and renal epithelial pathology.

The product is supplied at 1 mg/ml in phosphate buffered saline (PBS, pH 7.2) containing 0.05% sodium azide as a preservative, and ships as a 50 µl vial. The polyclonal rabbit host and unconjugated format make it compatible with secondary antibody detection systems of the researcher's choice, and the reagent has been validated for western blot, immunohistochemistry, and immunofluorescence against human, mouse, and rat samples.

Typical laboratory use includes staining kidney sections to delineate proximal and distal tubules, screening renal cell carcinoma tissue microarrays, and probing epithelial-to-mesenchymal transition in fibrosis models. The polyclonal nature broadens epitope coverage across the cadherin-16 ectodomain, supporting robust signal in immunohistochemistry on formalin-fixed sections. For storage, keep the vial refrigerated; aliquot upon first use to limit repeated freeze-thaw cycles and preserve antibody activity over the working shelf life of the stock.