Anti-CACNG4 Antibody

The CACNG4 polyclonal antibody from Antibodies.com targets the Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 4, a transmembrane AMPA receptor regulatory protein (TARP gamma-4) involved in excitatory synaptic transmission within central nervous system neurons. This rabbit polyclonal IgG reagent supports neuroscience workflows investigating glutamate receptor trafficking, ion channel modulation, and postsynaptic membrane organization across human, mouse, and rat sample types.

Supplied as a 100 µL liquid aliquot in a vial, the unconjugated antibody is validated for Western blot and immunofluorescence detection. It performs reliably on neuronal cell lines, primary neuron cultures, and brain tissue lysates, where researchers examine endogenous CACNG4 protein levels and subcellular localization. The polyclonal format provides broader epitope coverage for probing conserved regions of this neuronal auxiliary subunit, including within disease models relevant to excitatory synapse biology and altered neuronal signaling.

For Western blot, the unconjugated IgG pairs cleanly with standard HRP- or fluorescence-conjugated secondary antibodies, while the unconjugated format also enables multicolor immunofluorescence panel design. Refrigerated storage at 4°C preserves antibody activity for routine use, and aliquoting limits freeze-thaw cycles over the working life of the reagent. Antibodies.com supplies this primary antibody as part of their catalog of research reagents for ion channel and synaptic protein studies.