Anti-CACNB4 Antibody

This rabbit polyclonal antibody from Antibodies.com targets CACNB4, the voltage-gated calcium channel auxiliary subunit beta 4. Raised in rabbit and purified as an IgG preparation, the unconjugated reagent is supplied in a 200 µl vial and validated for Western blot detection across human, mouse, and rat samples.

CACNB4 modulates the gating and trafficking of P/Q-type and N-type calcium channels expressed throughout the central nervous system, and variants in the CACNB4 gene have been linked to episodic ataxia and idiopathic generalized epilepsy. Polyclonal reagents of this kind are commonly used to track expression of the approximately 58 kDa beta subunit across rodent and human brain tissue, where broader epitope coverage helps resolve the full-length protein on Western blots alongside an HRP- or fluorophore-conjugated secondary antibody.

Keep the vial refrigerated and aliquot on receipt to limit freeze-thaw cycles, protecting the solution from light between uses. Storing working aliquots separately from the stock vial preserves reagent activity across multiple experiments, and the unconjugated format gives users flexibility to pair the antibody with the detection chemistry of their choice.