Anti-CACNA1G Antibody

Raised in rabbit against the CACNA1G pore-forming α1G subunit of the Cav3.1 T-type voltage-gated calcium channel, this unconjugated polyclonal reagent is supplied by Antibodies.com as a 100 µl aliquot at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide, pH approximately 7.2. The antibody binds a conserved intracellular region of CACNA1G and has been validated for Western blot detection of the endogenous channel in lysates prepared from human, mouse, and rat tissues, supporting studies of low-threshold calcium signaling in neurons, cardiac pacemaker cells, and endocrine tissue. Researchers use it to probe the expression and post-translational regulation of Cav3.1 channels linked to neuronal firing patterns, absence epilepsy, pain pathways, and rhythmic activity in the sinoatrial node. The polyclonal format increases the likelihood of recognizing multiple CACNA1G isoforms, including the longer α1G-B and α1G-C variants that predominate in the brain. For short-term use the working stock should be refrigerated; for long-term storage, aliquot and freeze at -20°C to limit freeze-thaw cycles and protect from light, given the sodium azide preservative. Each vial is shipped from Antibodies.com ready to dilute into standard Western blot blocking and antibody dilution buffers.