Anti-CACNA1B Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com targets CACNA1B, the pore-forming alpha-1B subunit of the voltage-gated N-type calcium channel Cav2.2. Supplied as 100 µl, the reagent is validated for Western blot (WB) and immunofluorescence (IF) workflows on human samples. The polyclonal format recognizes multiple epitopes on the target, supporting detection of full-length channel subunits and partial isoforms in neuronal lysates and tissue sections. Cav2.2 channels drive presynaptic calcium influx that triggers neurotransmitter release at many central and peripheral synapses, so CACNA1B antibodies are widely used in neuroscience research on pain pathways, synaptic transmission, and inherited channelopathies. The unconjugated format lets researchers pair the antibody with custom fluorophores, horseradish peroxidase, biotin, or gold reporters depending on the application. Aliquot on arrival and store at -20 °C to limit freeze-thaw cycles of the polyclonal stock, and protect fluorescent-labelled working solutions from light during immunofluorescence protocols.