Anti-CABLES2 Antibody

This rabbit-derived polyclonal reagent from Antibodies.com targets the CABLES2 (CDK5 and ABL1 enzyme substrate 2) protein, a regulator implicated in cell cycle exit, neuronal differentiation, and apoptotic signalling pathways. Raised in Rabbit and supplied as an IgG antibody in unconjugated format, the reagent is validated for Western blot (WB) detection in human and mouse samples. Each vial contains 100 µl of antibody, supporting multiple immunoblotting experiments under standard laboratory conditions.

CABLES2 acts as a downstream effector that modulates CDK5 and ABL kinase activity, and altered expression has been reported in studies of cortical development and certain tumour contexts. The polyclonal nature of the reagent allows recognition of multiple epitopes on the target, which can be advantageous when probing endogenous CABLES2 levels across different tissue lysates. Researchers studying neurogenesis, cell cycle regulators, or kinase signalling cascades can use this reagent to characterise expression patterns in lysates derived from human and murine sources.