Anti-Cables1 Antibody

Cables1, also known as CDK5 and ABL1 enzyme substrate 1, is a regulator of the G1/S cell cycle checkpoint that interacts with CDK5 and ABL1 kinases and has been characterized as a tumor suppressor in colorectal, endometrial, and head and neck squamous cancers. This rabbit polyclonal reagent from Antibodies.com is supplied as 100 µl of unconjugated antiserum and is validated for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows in both human and mouse sample backgrounds. Researchers studying cell cycle control, CDK5-dependent signaling, or loss-of-function mechanisms in tumor biology can use the antibody to probe endogenous Cables1 expression across fixed sections and lysate preparations, supporting studies that link reduced Cables1 activity to abnormal proliferation.