Anti-CAB39L Antibody

This unconjugated rabbit polyclonal reagent from Antibodies.com targets CAB39L, a scaffold protein best known for its role in the LKB1-STRAD-MO25 complex that supports AMPK activation and cellular energy balance. Raised in rabbit and affinity-purified, the antibody is supplied as 100 µl of ready-to-use liquid in a single vial and is validated for western blot and immunohistochemistry on human samples.

The immunogen corresponds to a region of the human CAB39L sequence, and reactivity has been confirmed against human tissue. For western blot, clear bands are typically observed in lysates from cell lines and primary cells expressing the scaffold. In IHC, the antibody produces cytoplasmic staining consistent with the known distribution of CAB39L, which makes it a useful tool for studies of metabolic regulation, kinase signaling, and tumor biology where LKB1-AMPK pathways are under investigation.

Storage is straightforward: aliquot upon receipt and store at -20 °C for long-term use, avoiding repeated freeze-thaw cycles; for short-term work keep the vial refrigerated at 4 °C. The reagent is intended for research use only, supporting applications such as western blot (WB) and immunohistochemistry (IHC) in human samples, and pairs well with secondary antibodies of the user's choice given its unconjugated format.