Anti-CA XII Antibody

Carbonic anhydrase XII (CA XII) is a transmembrane zinc metalloenzyme involved in pH regulation, ion transport, and acidification of the tumor microenvironment. This polyclonal antibody from Antibodies.com was raised in rabbit and supplied as 100 µl of unconjugated antiserum, validated for western blot and ELISA workflows against human, mouse, and rat samples. The cross-species reactivity makes the reagent useful for comparative studies in cancer biology, renal physiology, and hypoxia research, where investigators probe carbonic anhydrase expression in epithelial tissues and tumor models. Because the reagent is polyclonal, it recognizes multiple epitopes on the CA XII target, which is helpful when working with denatured protein on membranes or when the antigen shows minor variability between samples. The unconjugated format gives researchers flexibility to pair the antibody with HRP, fluorescent, or biotin-labeled secondary reagents depending on the chosen detection platform. Store the vial refrigerated; aliquot upon arrival to limit freeze-thaw cycles and preserve antibody activity across multiple experiments. For research use only.