Anti-C4 Antibody [KT29]

The Antibodies.com Anti-C4 Antibody [KT29] is a Mouse monoclonal IgG1 reagent supplied as a 200 µg liquid preparation, validated for ELISA detection of human complement component C4. Clone KT29 recognizes a neoepitope that becomes exposed on the C4 activation fragment (C4b), so the antibody preferentially reports classical pathway activation rather than only baseline circulating C4 levels. This selectivity is relevant to research into immune complex deposition, autoimmune disease, transplant rejection, and biomarker assay development, where measuring cleavage products is more informative than total antigen quantification. For routine handling, store the vial frozen at -20 °C in small aliquots to limit freeze-thaw cycles and preserve binding activity across multiple ELISA microplates.