Anti-C3AR1 Antibody

Complement component 3a receptor 1 (C3AR1) is a G protein-coupled receptor expressed on mast cells, eosinophils, neutrophils, and selected neuronal populations, where it transduces signals from the complement anaphylatoxin C3a. This polyclonal reagent from Antibodies.com was raised in rabbit and is affinity-purified against a region of human C3AR1, supporting detection in both human and mouse samples.

Validated uses include Western blot for analysis of receptor expression in cell lysates and tissue homogenates, and immunohistochemistry for receptor localization in formalin-fixed, paraffin-embedded sections. The unconjugated format allows flexible pairing with multiple secondary antibody options for chromogenic or fluorescence detection. Each vial provides 100 µl of stock antiserum, generally sufficient for multiple blotting and staining experiments depending on working dilution.

C3AR1 is a frequent marker in inflammation and immunology studies, including research on asthma, sepsis, autoimmune disease, and complement-driven neurodegeneration. Investigators examining complement-mediated myeloid recruitment, microglial activation, or receptor upregulation in inflammatory lesions use this target for both qualitative and semi-quantitative readout.