Anti-C21orf33 Antibody

C21orf33 is a chromosome 21-encoded mitochondrial protein implicated in mitochondrial translation, ribosome assembly, and respiratory chain function. This rabbit polyclonal reagent from Antibodies.com specifically recognizes the human C21orf33 target in western blot and immunofluorescence workflows, supporting detection of endogenous protein levels in cell lysates and visualization of subcellular distribution in fixed cells. Provided as 100 µl of unconjugated antiserum raised in rabbit, the antibody is validated for human samples and enables researchers studying mitochondrial biogenesis, chromosome 21-linked aneuploidies such as Down syndrome, and oxidative phosphorylation deficiency to characterize expression patterns in relevant cell lines and primary cultures. The polyclonal format increases the likelihood of recognizing multiple epitopes on the target, which is particularly useful when probing low-abundance mitochondrial proteins or working with samples where post-translational modifications may mask individual epitopes. Intended for research use only, the reagent is suited to immunofluorescence-based subcellular localization studies and western blot analysis of enriched mitochondrial fractions, where it can complement studies of mitochondrial DNA translation, mitochondrial morphology, and respiratory supercomplex assembly in disease models.