Anti-C1S Antibody

C1S encodes the serine protease catalytic subunit of the C1 complex that initiates the classical complement pathway by cleaving complement components C4 and C2.

This unconjugated polyclonal reagent from Antibodies.com is raised in rabbit and validated for Western blot and immunohistochemistry on human tissue samples. Provided as a 100 µl aliquot, the antibody binds the native C1s protein, enabling detection of complement activation in hepatic, immunological, and connective-tissue research contexts.

The reagent supports studies investigating periodontal Ehlers-Danlos syndrome, classical pathway dysregulation, and inflammatory disease models where C1s expression and processing are of interest. Storage conditions generally recommend aliquoting to limit freeze-thaw cycles and protecting from light for long-term stability.