Anti-C1QB Antibody

The Complement C1q B chain (C1QB) is a structural subunit of the C1q complex, the recognition component of the classical complement activation pathway. This rabbit polyclonal antibody, supplied by Antibodies.com, detects endogenous C1QB in human and murine samples and is validated for Western blot and immunohistochemistry workflows. The unconjugated reagent is provided in a 100 µl volume, allowing multiple immunoblots or staining experiments per vial.

C1QB plays a central role in initiating complement-mediated lysis and clearance of immune complexes, with loss-of-function variants linked to C1q deficiency and early-onset systemic lupus erythematosus. Researchers investigating glomerulonephritis, neurodegeneration, or innate immune signaling commonly use C1QB antibodies to map tissue distribution and expression changes in disease models.

Aliquot upon first use and store refrigerated to preserve long-term reactivity.