Anti-C11orf30 Antibody

C11orf30, also known by the gene symbol EMSY, is a nuclear protein implicated in chromatin remodeling, the DNA damage response, and transcriptional regulation through its interaction with trimethylated histone H3 lysine 36 (H3K36me3). This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against the human C11orf30 target and is supplied as 100 µl of affinity-purified antibody for Western blot and immunofluorescence workflows.

The antibody supports detection of endogenous C11orf30 in cell lysates and fixed-cell preparations, making it useful for studies of homologous recombination repair, BRCA2-pathway biology, and amplification patterns reported in breast and ovarian cancer research. Because EMSY functions as a transcriptional repressor that recruits chromatin-modifying complexes, validated antibodies against it are commonly used in epigenetics, chromatin biology, and DNA repair investigations.

For handling, the antibody should be aliquoted upon receipt to limit repeated freeze-thaw cycles and stored frozen at -20 °C in a suitable buffer to preserve activity across multiple experiments. Lot-specific validation data and supporting documentation are available from Antibodies.com.