Anti-c-Src Antibody

Raised in rabbit as a polyclonal reagent, this unconjugated primary antibody from Antibodies.com targets the c-Src proto-oncogene, a 60 kDa non-receptor tyrosine kinase encoded by SRC. c-Src sits at the intersection of integrin, focal adhesion kinase, and receptor tyrosine kinase signaling cascades, phosphorylating substrates that govern cell adhesion, proliferation, migration, and survival. It is therefore a focal point of cancer biology research, particularly in studies of triple-negative breast cancer, colorectal carcinoma, and head-and-neck squamous cell carcinoma, as well as bone remodeling, platelet biology, and immune cell receptor signaling.

Validated for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows, the reagent recognizes c-Src orthologs from human, mouse, and rat sources, supporting cross-species studies that span cultured cell panels and primary tissue specimens. Each vial is supplied at 100 µl as an unconjugated preparation, allowing researchers to pair it with their preferred secondary antibody and detection chemistry across a wide variety of experimental designs.