Anti-c-Myb Antibody

From Antibodies.com, this rabbit polyclonal primary antibody specifically targets the c-Myb transcription factor, a MYB family proto-oncogene product implicated in hematopoietic lineage commitment and progenitor cell self-renewal. Supplied as 100 µl of unconjugated antiserum, the reagent supports detection of endogenous c-Myb in Western blot and ELISA workflows against Human and Mouse sample backgrounds.

The c-Myb protein plays a pivotal role in chromatin-mediated transcriptional regulation and is a recognized contributor to leukemia biology, immune cell development, and oncogenic signaling pathways. Polyclonal antibodies raised in rabbit typically recognize multiple epitopes across the target, providing broader detection when antigen expression is low or when post-translational modifications might mask a single recognition site.

The unconjugated format allows flexibility for downstream labeling with HRP, fluorescent dyes, or biotin depending on the experimental readout. Researchers can aliquot the 100 µl volume into single-use portions to limit freeze-thaw cycles and preserve antibody activity during long-term storage, supporting reproducible results across multiple experiments.