Anti-c-kit (phospho Tyr719) Antibody

Phospho-specific detection of activated c-kit (CD117/SCFR) receptor tyrosine kinase is supported by this rabbit polyclonal IgG reagent from Antibodies.com, supplied as 100 µg of lyophilised powder that reconstitutes cleanly for bench use. The antibody binds the phospho-Tyr719 epitope, an autophosphorylation site that couples c-kit to downstream PI3K/Akt signalling after stem cell factor (SCF) engagement. Confirmed reactivity covers mouse and human samples, supporting studies of mast cell biology, hematopoietic stem cell regulation, and gastrointestinal stromal tumour (GIST) research where aberrant c-kit activity is a focus. The unconjugated format gives flexibility to pair with HRP, fluorophore, or biotin reporters in ELISA and related immunoassay workflows, while aliquoting the reconstituted antibody preserves binding activity through repeated freeze-thaw cycles.