Anti-c-Kit Antibody

Raised in rabbit as a polyclonal reagent, this unconjugated primary antibody targets c-Kit (also called CD117), the receptor tyrosine kinase whose ligand is stem cell factor. Researchers rely on it to track KIT signaling in hematopoietic, melanocyte, and mast cell biology, and to characterize c-Kit expression in tumor specimens — notably gastrointestinal stromal tumors (GIST) and mastocytosis lesions — by western blot and immunohistochemistry, with ELISA also supported. The Antibodies.com antibody cross-reacts with human and mouse samples, making it a practical choice for translational studies that span patient tissue and murine disease models. Supplied at 100 µL in a single vial, it integrates cleanly into standard immunostaining and immunoblotting protocols without requiring a secondary conjugation step before detection.