Anti-c-Kit Antibody

This recombinant rabbit monoclonal antibody recognizes the c-Kit receptor tyrosine kinase (also called CD117 or KIT), a transmembrane signaling protein expressed on hematopoietic stem cells, mast cells, melanocytes, germ cells, and the interstitial cells of Cajal in the gastrointestinal tract. From Antibodies.com, the unconjugated reagent is validated for Western blot (WB) and immunohistochemistry (IHC) on human tissue, supporting research applications in gastrointestinal stromal tumor (GIST) pathology, systemic mastocytosis, mast cell biology, acute myeloid leukemia immunophenotyping, melanoma studies, and hematopoietic stem cell characterization.

Each vial contains 100 µl of recombinant antibody in 1× TBS (pH 7.4) with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative, allowing direct pairing with labeled secondary antibodies of the researcher's choice. Short-term storage at 4 °C is acceptable for working aliquots, while long-term storage at -20 °C preserves binding activity for ongoing studies of tyrosine kinase signaling, stem cell biology, and melanocyte development.