Anti-c-Jun (Ab-243) Antibody

c-Jun is a key transcription factor that forms the activator protein-1 (AP-1) complex with c-Fos and related partners, regulating gene programs for cell proliferation, differentiation, apoptosis, and the cellular stress response. This rabbit polyclonal reagent from Antibodies.com is raised against c-Jun at the Ab-243 epitope region and supports studies of AP-1 signaling and stress-activated transcription across multiple model systems.

Validated for western blot (WB) and immunohistochemistry (IHC), the antibody cross-reacts with c-Jun from human, mouse, and rat samples, enabling comparative work in cell line and tissue-based experiments. It is supplied as 100 µl of unconjugated antiserum in a vial format; the polyclonal response recognizes multiple epitopes on the target and is compatible with user-selected secondary antibody detection systems.

Common research applications include investigations of AP-1-driven transcription in cancer biology, neuronal injury responses, and developmental signaling, where c-Jun expression and phosphorylation status serve as readouts of upstream kinase activity, including JNK pathway engagement.