Anti-c-Jun (Ab-239) Antibody

c-Jun, a core subunit of the AP-1 (activator protein-1) transcription factor complex, is recognized by a rabbit polyclonal reagent from Antibodies.com. c-Jun dimerizes with Jun and Fos family partners to bind TRE/AP-1 DNA response elements, where it directs transcription of genes governing cell proliferation, differentiation, and apoptosis in response to growth factors, cytokines, and stress cues.

The 100 µL unconjugated polyclonal antibody supports Western blot and immunohistochemistry workflows on human, mouse, and rat samples. Recognition of multiple epitopes across the target allows detection of denatured c-Jun on Western blot membranes and of fixed c-Jun within tissue sections, including formalin-fixed paraffin-embedded specimens prepared for chromogenic staining.

As an unconjugated primary reagent, this antibody is paired with the investigator's choice of secondary detection system, including HRP-conjugated, biotinylated, or fluorescent secondaries. This adaptability accommodates chemiluminescent Western blot readouts, immunohistochemistry on paraffin or frozen sections, and immunofluorescence localization studies in cell and tissue preparations.