Anti-c-Cbl (Ab-700) Antibody

Raised in rabbit, this unconjugated polyclonal antibody from Antibodies.com targets a region of human c-Cbl centred around residue 700 (Ab-700). c-Cbl is a multi-domain E3 ubiquitin ligase and adaptor protein that tags activated receptor tyrosine kinases for endocytic clearance and dampens signalling downstream of T-cell, B-cell, and cytokine receptors, which is why it remains a focal point of signal-transduction, immunology, and oncology research. The reagent is supplied as 100 µl of polyclonal antibody, validated for Western blot (WB) and immunohistochemistry (IHC) on human tissue and cell-line samples. Because it is unconjugated, the antibody can be paired with HRP, biotin, alkaline phosphatase, or fluorescent secondaries to suit the chosen workflow. Each vial should be stored at -20 °C in working aliquots to limit freeze-thaw damage, and the product is intended for research use only.