Anti-BVES Antibody

BVES (Blood Vessel Epicardial Substance), also known as POPDC1, is a transmembrane protein of the Popeye domain-containing family that supports cell-cell adhesion, cyclic nucleotide signalling, and maintenance of cardiac and skeletal muscle architecture. The unconjugated Rabbit polyclonal antibody to BVES from Antibodies.com is affinity-purified and supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a stabilising cryoprotectant. Each 100 µl vial delivers enough reagent to run multiple western blot and immunohistochemistry experiments, and the antibody has been validated for reactivity against human, mouse, and rat samples.

BVES localises to the plasma membrane and is enriched in heart tissue, smooth muscle, and epithelial junctions, where it associates with the underlying cytoskeleton and participates in intercellular adhesion complexes. Researchers studying arrhythmogenic cardiomyopathy, epithelial barrier function, and skeletal muscle regeneration use this reagent to probe endogenous expression, map tissue distribution, and characterise interacting partners such as caveolin and the MAGI family of scaffolding proteins.

The polyclonal host format allows recognition of multiple epitopes on the BVES target, which is useful when working with samples that may carry post-translational modifications or alternative splice products. Store the vial refrigerated and protect it from light to preserve antibody activity; this product is intended for research use only and is not validated for diagnostic or therapeutic procedures.