Anti-BTN3A1 Antibody

Rabbit polyclonal IgG antibody raised against human butyrophilin subfamily 3 member A1 (BTN3A1), supplied by Antibodies.com as an unconjugated reagent in a 200 µL volume validated for western blot workflows. BTN3A1 is a type I transmembrane immunoglobulin-like protein that functions as an intracellular phosphoantigen sensor licensing Vγ9Vδ2 γδ T cell activation, making this reagent useful for studies in cancer immunotherapy, immune surveillance, and γδ T cell biology.

Generated in rabbit and purified as a polyclonal IgG, the antibody recognizes multiple epitopes on the human target, supporting expression profiling and mechanistic work in western blot. The unconjugated presentation offers flexibility for downstream labeling and detection strategy selection in the lab, with reactivity restricted to human samples. Researchers investigating phosphoantigen-driven γδ T cell responses, tumor-infiltrating lymphocytes, and the broader butyrophilin/B7 family of immunomodulatory proteins will find this antibody applicable to characterizing BTN3A1 expression in cell lines and primary tissue lysates.