Anti-BTN1A1 Antibody

This rabbit polyclonal antibody targets BTN1A1 (Butyrophilin subfamily 1 member A1), a type I transmembrane glycoprotein best known for its role in milk lipid droplet secretion from mammary epithelial cells during lactation. Raised in rabbits and affinity purified, the reagent is supplied as an unconjugated IgG preparation at 50 µl per vial, suitable for direct labeling or downstream detection chemistries in Western blot workflows.

BTN1A1 belongs to the B7-like butyrophilin family of immunomodulatory molecules and has been investigated in the context of epithelial-microbial interactions, T cell costimulation, and certain solid tumor studies, including breast cancer research. The antibody is validated on mouse and rat samples, allowing cross-species comparison in tissue homogenates and cell-based experiments. Researchers commonly apply it in chemiluminescent or fluorescent Western blot detection of endogenous BTN1A1 expression in lactating mammary gland and other target tissues.

For best results, aliquot the antibody upon arrival to limit freeze-thaw cycles, store at -20 °C in working aliquots, and protect from light between uses. The unconjugated format from Antibodies.com gives laboratories flexibility to pair it with HRP, biotin, or fluorophore-conjugated secondary antibodies of their own choosing, adapting the protocol to their preferred imaging system.