Anti-BRSK1 Antibody

This rabbit polyclonal antibody targets BRSK1 (BR Serine/Threonine Kinase 1), a brain-enriched kinase linked to neuronal polarization, centrosome duplication, and G2/M cell cycle checkpoint control. Raised in rabbit and purified as an unconjugated IgG, the reagent is supplied by Antibodies.com as a 200 µL liquid aliquot and is validated for Western Blot detection of endogenous BRSK1 in human and mouse samples.

BRSK1, also called SAD1 or SAD-B, is highly expressed in neurons and pancreatic islets and has been studied in the contexts of synaptic vesicle trafficking, metabolic regulation, and mitotic signaling. Because the kinase migrates around 85 kDa on SDS-PAGE, the antibody is well suited to immunoblotting of whole-cell lysates from neuronal cell lines, brain tissue, or transfected mammalian cells. The polyclonal format provides broad epitope coverage for monitoring expression levels, phosphorylation state, and isoform distribution across tissues.

Recommended handling includes brief centrifugation of the vial before opening, short-term storage at 4 °C, and aliquoting with freezing at -20 °C for longer term use to minimize freeze-thaw cycles. Researchers working on neurodegeneration, diabetes models, and cell cycle signaling can use this reagent in standard Western Blot workflows to probe BRSK1 abundance in lysates prepared from cultured cells or tissue.