Anti-BRS3 Antibody

BRS3 (Bombesin Receptor Subtype 3) is a G protein-coupled receptor involved in appetite regulation, energy balance, and glucose homeostasis. Loss-of-function studies in rodent models link BRS3 deficiency to hyperphagia, obesity, and impaired insulin response, making the receptor a recurring target in metabolic disease and neuroendocrinology research. This unconjugated rabbit polyclonal reagent from Antibodies.com was raised against the human BRS3 sequence and recognizes an epitope conserved across human, mouse, and rat orthologues. The antibody is supplied as 100 µl of affinity-purified antiserum and is validated for Western blot and immunohistochemistry on formalin-fixed, paraffin-embedded tissues. Investigators working on bombesin receptor pharmacology, hypothalamic feeding circuits, or pancreatic islet signaling commonly pair this reagent with peptide-block controls to confirm band specificity. The polyclonal format offers broader epitope coverage than monoclonal alternatives, supporting detection of the full-length receptor as well as shorter receptor fragments described in published studies. Storage at -20 °C in working aliquots preserves activity across repeated freeze-thaw cycles. For research use only; not intended for diagnostic or therapeutic applications.