Anti-BRM Antibody

The SWI/SNF chromatin remodeling complex plays a central role in regulating gene expression, and BRM (also called SMARCA2) serves as one of its two mutually exclusive catalytic ATPase subunits. This unconjugated rabbit polyclonal reagent from Antibodies.com was raised against BRM and validated for Western blot detection in human, mouse, and rat samples. It is supplied as a 100 µL vial of 1 mg/ml stock in PBS containing 0.1% sodium azide and 50% glycerol, ready to dilute into standard immunoblotting workflows. Researchers commonly apply it to studies of chromatin remodeling, transcriptional regulation, and cancer biology, where loss of BRM expression has been linked to tumor progression and altered lineage commitment in lung, gastric, and other solid tissues. The polyclonal format provides recognition of multiple epitopes on the target protein, which can help maintain signal across different sample preparations and lysis conditions commonly used for chromatin-associated factors.