Anti-BRD9 Antibody

Bromodomain-containing protein 9 anchors the ncBAF (non-canonical BAF) chromatin remodeling complex and is a focus of cancer research, particularly in synovial sarcoma where the SS18-SSX fusion disrupts normal BRD9 occupancy, in acute myeloid leukemia, and in prostate cancer models. This Antibodies.com reagent is a rabbit polyclonal antibody supplied as a 100 µL unconjugated aliquot and validated for western blot and immunohistochemistry on human and mouse samples. Investigators apply it to map BRD9 distribution across SWI/SNF subtype compositions, validate degrader and inhibitor efficacy in cell culture systems, and probe transcriptional programs dependent on bromodomain reader activity. The antibody performs well across whole-cell lysates and formalin-fixed tissue sections, supporting both protein-level expression studies and chromatin fractionation workflows. For best results, aliquot upon arrival, store refrigerated, protect from light, and minimize freeze-thaw cycles to maintain polyclonal reactivity over multiple experiments.