Anti-BRD2 Antibody

This polyclonal antibody targets Bromodomain-containing protein 2 (BRD2), a chromatin reader belonging to the BET (bromodomain and extra-terminal motif) family that recognizes acetylated lysine residues on histone tails through its tandem bromodomains. Produced in rabbit and supplied as an IgG preparation at 100 µl, the reagent supports research workflows examining transcriptional regulation, chromatin biology, and chromatin-associated signaling.

Validated applications include Western blot and immunohistochemistry, supporting detection of endogenous BRD2 in human samples and in expression studies characterizing the BET family. The unconjugated format allows researchers to choose their own detection chemistry, including HRP, biotin, or fluorophore labeling, depending on the assay design.

BRD2 has become a focal target in studies of bromodomain inhibition, cell-cycle progression, and oncogenic transcription programs associated with B-cell lymphoma, leukemia, and certain solid tumors. Investigators using this polyclonal reagent from Antibodies.com can probe full-length BRD2 expression and bromodomain-dependent chromatin interactions in cell lines, primary tissue, and disease-model systems.