Anti-BRCA1 (phospho S1423) Antibody

A rabbit polyclonal IgG antibody targeting BRCA1 phosphorylated at Serine 1423, offered unconjugated by Antibodies.com within the Primary Antibodies range. Raised in rabbit and validated for Western blot, immunohistochemistry, and immunofluorescence (ICC/IF) applications, it reacts with Human, Mouse, and Rat samples.

The immunogen is a synthetic phosphorylated peptide surrounding Serine 1423 of human BRCA1 (NP_009225.1), and the reagent is affinity-purified. It is supplied as a liquid in Phosphate Buffered Saline (pH 7.3) with 50% glycerol and 0.02% sodium azide. The product is shipped at 4 °C and upon delivery should be aliquoted and stored at -20 °C, with freeze/thaw cycles to be avoided. Recommended dilutions are WB 1:500–1:2,000, IHC 1:50–1:200, and ICC/IF 1:50–1:200.

The target is BRCA1, with a reported molecular weight of 270 kDa, and the modification recognised is phospho-Ser1423.