Anti-BRCA1 Antibody

BRCA1 is a critical tumor suppressor protein involved in DNA double-strand break repair through homologous recombination, and germline mutations in the BRCA1 gene are strongly associated with hereditary breast and ovarian cancer susceptibility. This unconjugated rabbit polyclonal reagent from Antibodies.com targets the human BRCA1 protein for detection across multiple experimental platforms including Western blotting, immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, and ELISA-based assays. The antibody is supplied as a 50 µl aliquot of polyclonal antiserum raised in rabbit, with reactivity confirmed against human BRCA1 epitopes. Researchers studying DNA damage response pathways, hereditary cancer predisposition, or tumor suppressor biology routinely use BRCA1 antibodies to evaluate protein expression in patient-derived samples and cell line models. The unconjugated format allows flexible pairing with secondary antibodies and custom detection chemistries suited to specific laboratory workflows.