Anti-BRCA1 Antibody

This rabbit polyclonal reagent from Antibodies.com targets the BRCA1 tumor suppressor, a key regulator of homologous recombination repair that localizes to nuclear foci following DNA damage and partners with RAD51 at double-strand break sites. Validated for western blot, immunohistochemistry, and immunofluorescence workflows, the unconjugated antibody supports detection of endogenous human BRCA1 in cell lysates, formalin-fixed tissue sections, and cultured cells. The 100 µl format provides sufficient volume for multiple replicate experiments and titration optimization across standard immunoblotting and imaging protocols. Researchers studying hereditary breast and ovarian cancer susceptibility, DNA damage response signaling, and genome stability pathways can apply this reagent to investigate BRCA1 expression patterns, phosphorylation events, and functional interactions in research use only settings.