Anti-BRCA1 Antibody

A polyclonal antibody raised in rabbit is available from Antibodies.com for the detection of BRCA1, a tumor suppressor protein encoded by the BRCA1 gene that plays a central role in homologous recombination repair of DNA double-strand breaks and is widely studied in hereditary breast and ovarian cancer susceptibility research.

The unconjugated reagent is supplied in a 100 µl volume and supports western blot, immunohistochemistry, immunofluorescence, and ELISA workflows. Reactivity has been validated against human and rat samples, making the antibody useful for cross-species investigations of cancer biology, genome stability, and the DNA damage response.

For best results, aliquot the antibody upon arrival and store refrigerated; avoid repeated freeze-thaw cycles to preserve binding activity. This research-use-only reagent enables detection of endogenous BRCA1 expression across cell-based and tissue-based assays and complements downstream applications such as co-immunoprecipitation studies of BRCA1-containing repair complexes.