Anti-BRAF Antibody

Recognizing the B-Raf proto-oncogene serine/threonine kinase, this unconjugated polyclonal antibody preparation from Antibodies.com is validated for both Western blot (WB) and immunohistochemistry (IHC) applications across human, mouse, and rat samples. The reagent targets BRAF, a key regulator of the MAPK/ERK signaling cascade that controls cell proliferation, differentiation, and survival, making it useful for studies of cancer biology and signal transduction.

Raised in rabbits and supplied at 100 µl per vial, the antibody leverages a polyclonal response that recognizes multiple epitopes on the target protein, broadening detection of variant forms and clinically relevant mutants such as the V600E alteration frequently investigated in melanoma, colorectal, and thyroid carcinoma research. The unconjugated format allows pairing with user-preferred HRP, biotin, or fluorescent secondary detection chemistry, while the cross-reactivity profile supports comparative work in three commonly used mammalian model organisms and human tissue specimens. Aliquot on first use, refrigerate, and avoid repeated freeze-thaw cycles to preserve binding activity through the working shelf life.