Anti-BNC2 Antibody

This unconjugated polyclonal reagent from Antibodies.com is raised in rabbit against Basonuclin 2 (BNC2), a zinc-finger protein expressed in epithelial tissues and involved in chromatin-associated gene regulation. Published genome-wide studies have linked BNC2 variants to ovarian cancer susceptibility, and the protein has been studied in the context of epithelial cell differentiation programs relevant to keratinocyte and mucosal biology.

The antibody is supplied as 100 µl of IgG in a vial format and is validated for Western blot detection of the mouse target. The polyclonal format recognizes multiple epitopes across the BNC2 sequence, which is useful when probing full-length and shorter isoforms on the same membrane, or when single-epitope affinity is limiting for downstream immunoblotting of cell and tissue lysates.

Recommended handling includes brief equilibration to room temperature before use and storage refrigerated between experiments to preserve reagent activity across repeated blotting runs. Each lot is calibrated for use with standard SDS-PAGE transfer workflows and chemiluminescent or fluorescent readouts on nitrocellulose or PVDF membranes, supporting reproducible band detection across a range of sample inputs.