Anti-BMPR2 Antibody

BMPR2 (Bone Morphogenetic Protein Receptor Type 2) is a serine/threonine kinase receptor in the TGF-β superfamily, central to SMAD-dependent signal transduction that governs vascular homeostasis, endothelial function, and pulmonary vascular remodeling. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against BMPR2 and validated for western blot and immunohistochemistry workflows across human, mouse, and rat sample backgrounds, making it a useful tool for studies of heritable pulmonary arterial hypertension, vascular biology, and bone formation pathways.

Each vial is supplied as 100 µl of polyclonal antiserum, suitable for direct use or further titration in standard immunodetection protocols. Researchers should aliquot upon receipt to limit freeze-thaw cycles, store refrigerated for short-term use, or keep frozen for longer-term retention protected from light. Detection in tissue sections by immunohistochemistry and protein-level analysis by western blot allow orthogonal confirmation of BMPR2 expression in cultured cells and in vivo models, supporting research use only investigations into receptor localization, signaling complex assembly, and downstream SMAD phosphorylation.