Anti-BMP-8B Antibody

Recognizing the bone morphogenetic protein BMP-8B, this unconjugated polyclonal reagent from Antibodies.com is raised in rabbit and supplied as a 100 µl liquid aliquot. BMP-8B, a member of the TGF-beta superfamily, participates in skeletal development, male germ cell maturation, and central nervous system patterning, where signaling through BMP-8B influences osteogenic differentiation, spermatogenesis, and neurogenesis.

Validated for Western blot and ELISA, the antibody detects endogenous human BMP-8B in cell and tissue lysates and supports quantitative measurement of the analyte in research samples. Reactivity is confirmed against human targets, and the polyclonal format provides broader epitope coverage than monoclonal alternatives, enabling recognition of multiple BMP-8B isoforms and processed forms of the ligand.

The unconjugated formulation allows researchers to conjugate the antibody with their preferred reporter dye, enzyme, or bead system, and the host species (rabbit) enables straightforward pairing with a wide selection of commercially labeled secondary reagents. For storage, aliquoting and freezing at -20 °C preserves activity across repeated freeze-thaw cycles. Recommended applications include expression profiling of BMP pathway components, knockdown validation studies, and characterization of developmental signaling cascades in human-derived cells and tissues.