Anti-BLMH Antibody

Bleomycin hydrolase (BLMH) is a cytoplasmic cysteine aminopeptidase that contributes to cellular protein turnover and the metabolic inactivation of bleomycin chemotherapy agents. This polyclonal antibody from Antibodies.com is raised in rabbit and supplied as an unconjugated IgG preparation in a 100 µL vial, ready for direct labeling or use in standard immunodetection workflows.

Validated applications include Western blot analysis of whole-cell lysates, immunohistochemistry on formalin-fixed tissue sections, and immunofluorescence staining of cultured cells. Cross-reactivity is confirmed against human, mouse, and rat samples, supporting translational work across commonly used model systems and clinical tissue research.

Typical use cases include studies of bleomycin resistance mechanisms in tumor cell lines, characterization of aminopeptidase activity in cellular homeostasis, and investigation of protein degradation pathways under oxidative or chemical stress. Pair with appropriate blocking reagents and secondary antibodies matched to the chosen detection method, such as HRP conjugates for chromogenic IHC, fluorophore-conjugated secondaries for IF imaging, or enzyme-linked reagents for Western blot membranes.