Anti-BIRC5 Antibody

Offered by Antibodies.com as a research-grade primary antibody, this rabbit polyclonal reagent targets BIRC5 (also known as Survivin), a member of the inhibitor of apoptosis (IAP) family implicated in cell-cycle regulation and apoptosis. The antibody was raised against a recombinant human BIRC5 immunogen and purified by affinity chromatography, and it detects endogenous levels of the total BIRC5 protein. It is supplied unconjugated at 1.0 mg/mL in 50 µl of phosphate-buffered saline (without Mg²⁺ and Ca²⁺), pH 7.4, containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol. The reagent is validated for Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) applications and cross-reacts with human, mouse, and rat samples, making it suitable for cross-species studies in apoptosis, oncology, and cell-division research. Shipping is on wet ice at 4 °C; on arrival the antibody should be aliquoted and stored at –20 °C, with repeated freeze/thaw cycles avoided to preserve activity. Routine use at 1:500–1:2000 for WB and 1:50–1:200 for IHC is typical for this product class.