Anti-BIRC2 Antibody - Identical to Abcam (ab196592)

The BIRC2 protein (also known as cIAP1) is a key regulator of apoptosis and NF-κB signaling, functioning as an E3 ubiquitin ligase that modulates TNF receptor-mediated pathways. This rabbit polyclonal antibody from Antibodies.com targets the baculoviral IAP repeat-containing 2 protein and is validated for Western blot detection in both human and mouse samples.

The unconjugated IgG reagent is supplied as 200 µl of polyclonal antiserum, intended for immunoblotting applications investigating apoptosis regulation, inflammatory signaling, and cancer research. Researchers use this reagent to study cIAP1 expression in tumor cell lines, to probe RIP1 ubiquitination downstream of TNF receptor activation, and to characterize IAP family member expression in knockout models.

For optimal performance, aliquot the antibody upon arrival and store at -20°C, avoiding repeated freeze-thaw cycles to preserve reagent activity. The polyclonal format provides recognition of multiple epitopes on the BIRC2 target, which can be advantageous for detecting the protein under varying expression conditions and across different sample preparations in research use only workflows.