Anti-BHMT Antibody

This polyclonal antibody from Antibodies.com targets betaine-homocysteine S-methyltransferase (BHMT), a zinc-dependent cytosolic enzyme expressed predominantly in liver and kidney tissue. The reagent is supplied as 100 µL of unconjugated rabbit antiserum, validated for western blot (WB) and immunohistochemistry (IHC) workflows. The polyclonal format enables recognition of multiple epitopes on the BHMT protein, which can strengthen signal across blots and tissue sections where epitope accessibility varies. Cross-reactivity with human, mouse, and rat samples makes the reagent useful for comparative studies of one-carbon metabolism, hepatic methylation capacity, and homocysteine remethylation pathways. Researchers modeling non-alcoholic fatty liver disease, methionine cycle disruption, or renal osmolyte handling routinely profile BHMT expression, and a polyclonal reagent offers flexibility for both denatured and partially native detection contexts. Storage guidance generally includes aliquoting upon receipt to limit freeze-thaw cycles, with refrigerated handling to preserve titer across repeated experiments.