Anti-BGLAP Antibody

This unconjugated polyclonal IgG reagent from Antibodies.com is raised in rabbit against human BGLAP, the gene encoding osteocalcin (bone Gla protein), a small secreted peptide produced by osteoblasts that is incorporated into the bone extracellular matrix and circulates as a metabolic hormone. Supplied at 100 µl per vial, the antibody is validated for Western blot (WB) and immunohistochemistry (IHC), making it applicable to studies of bone formation, osteoblast differentiation, and the endocrine roles of osteocalcin in glucose homeostasis. The polyclonal backbone broadens epitope recognition across both carboxylated and undercarboxylated forms, supporting use on fixed tissue sections from bone biopsies, mineralized cell culture models, and conditioned media from osteoblast cell lines. For handling, aliquot on receipt and store at -20 °C protected from light to preserve immunoreactivity across repeated freeze-thaw cycles, with the unconjugated format allowing flexible pairing with custom secondary detection reagents in either chromogenic or fluorescence workflows.