Anti-beta 2 Microglobulin Antibody [D3A2]

Beta 2 microglobulin (B2M) is a ~12 kDa non-covalently associated light chain of the major histocompatibility complex (MHC) class I molecule, expressed on the surface of nearly all nucleated cells. This unconjugated mouse monoclonal IgG1 antibody, clone D3A2, was raised against human B2M and is reactive with human samples.

Supplied by Antibodies.com as a lyophilised preparation at 100 µg per vial, the reagent is suited to ELISA, Western blot, immunofluorescence, and flow cytometry workflows. Reconstitute the lyophilised powder in an appropriate buffer before dilution into working stocks, and refrigerate the reconstituted material for short-term use. The lyophilised product should be protected from light during long-term storage.

Researchers working on MHC class I antigen presentation, lymphocyte surface phenotyping, kidney filtration markers, and multiple myeloma or lymphoma investigations routinely use B2M-specific antibodies for both detection and quantitation. As an unconjugated primary reagent, the antibody can be paired with a secondary detection system (HRP, fluorophore, or biotin conjugates) tailored to the chosen platform.