Anti-BDNF Antibody

Brain-Derived Neurotrophic Factor (BDNF) is a key neurotrophin widely studied in neuroscience research, where it is recognized for its roles in neuronal survival, synaptic plasticity, and the differentiation of central and peripheral neurons. This Antibodies.com primary antibody is a rabbit polyclonal reagent raised against BDNF and supplied in an unconjugated format in a 100 µl volume, ready for direct labeling or use in secondary detection workflows. The antibody is reactive across Human, Mouse, and Rat samples, supporting cross-species translational studies in rodent disease models and human tissue analysis. It has been validated for Western Blot and Immunohistochemistry, two widely used techniques for characterizing BDNF expression in brain tissue, peripheral samples, and cell lysates. Researchers commonly apply it to investigate BDNF involvement in neurodegenerative disease, mood disorders, learning and memory, neuroprotection studies, and developmental neuroscience. As a polyclonal reagent, the antibody targets multiple epitopes on BDNF, which can improve signal detection in samples where the target protein is expressed at low levels or has been partially degraded during processing.