Anti-BDNF Antibody

BDNF Polyclonal Antibody for Neuroscience Research

This rabbit polyclonal antibody from Antibodies.com targets brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family involved in neuronal survival, differentiation, and synaptic plasticity. The unconjugated reagent is supplied at 1 mg/mL in PBS with 0.1% sodium azide and 50% glycerol as a 100 µl vial, suitable for both western blot (WB) and immunohistochemistry (IHC) workflows.

BDNF is widely investigated in studies of hippocampal function, long-term potentiation, and memory formation, and the antibody's confirmed reactivity with human, mouse, and rat samples makes it practical for translational work spanning rodent disease models and human tissue. Researchers studying neurodegenerative conditions, mood disorders, and peripheral nerve injury frequently use anti-BDNF reagents to track expression changes in cortex, hippocampus, and dorsal root ganglia.

The polyclonal format provides multiple epitope recognition, which can help when monitoring full-length proBDNF (~32 kDa) and its mature ~14 kDa cleavage product on western blot. For IHC, the reagent supports visualisation of BDNF-expressing neurons in fixed brain sections. Store aliquots refrigerated at 4 degrees C for short-term use or freeze for longer-term stability, and protect from light to preserve activity across runs.