Anti-BDKRB2 Antibody

Bradykinin B2 receptor (BDKRB2) is a G protein-coupled receptor that mediates the vascular and inflammatory actions of bradykinin, a key peptide of the kallikrein-kinin system. This unconjugated rabbit polyclonal reagent is supplied by Antibodies.com as 100 µL of polyclonal antiserum, intended for Western blot (WB) and immunohistochemistry (IHC) workflows against human and mouse tissue samples.

The antibody is raised in rabbit and purified to recognize the native BDKRB2 sequence, making it a useful detection reagent for cardiovascular, vascular biology, and inflammation research. Because BDKRB2 signaling drives vasodilation, vascular permeability, and nociceptive responses, it is widely studied in models of angioedema, ACE inhibitor pharmacology, sepsis, and chronic inflammatory pain. Researchers applying this antibody on IHC can localize BDKRB2 in endothelial and smooth muscle compartments, while Western blot applications allow confirmation of receptor expression across tissues such as lung, kidney, and vascular beds.

The reagent is unconjugated and contains no fluorophore or enzyme label, so it pairs readily with HRP- or fluorophore-tagged secondary antibodies. Each vial ships as 100 µL of polyclonal antibody and is handled as a standard research-use-only reagent. As with all Antibodies.com primary antibodies, lot-to-lot consistency is monitored, and the reagent is intended for research use only.