Anti-BCL6 Antibody

BCL6 is a BTB/POZ-domain zinc-finger transcriptional repressor best known as the master regulator of germinal center B-cell identity, and this polyclonal reagent from Antibodies.com is raised in rabbit against the human protein. Supplied as 100 µl of unconjugated antiserum, the antibody is validated for western blot and immunohistochemistry on human samples, where it reliably marks centroblasts and centrocytes within reactive follicles and supports the workup of diffuse large B-cell lymphoma (DLBCL) and other germinal-center-derived neoplasms. Because BCL6 is also expressed by T follicular helper cells, the antibody is useful in studies of T-B collaboration, class-switch recombination, and DNA-damage responses in germinal centers. Researchers can pair it with CD10 and BCL2 to build a follicular-versus-diffuse panel for lymphoma subtyping, including nodular lymphocyte-predominant Hodgkin lymphoma and Burkitt lymphoma. The reagent is provided as an unconjugated polyclonal in a 100 µl vial volume, leaving secondary antibody, fluorophore, and chromogen choices open across WB and IHC workflows.