Anti-BCL2L10 Antibody

This polyclonal reagent targets BCL2L10, an anti-apoptotic member of the BCL-2 protein family also referred to as Diva and Boo. The protein localizes to mitochondria and modulates programmed cell death through interactions involving its BH1, BH2, BH3, and BH4 homology domains. Supplied by Antibodies.com as a 100 µl unconjugated preparation raised in rabbit, the antibody is validated for western blot, immunohistochemistry, and immunofluorescence detection of the human target. Investigators characterizing apoptotic regulation, mitochondrial biology, and tumor cell survival use this reagent to probe endogenous BCL2L10 expression in fixed tissue sections and cultured cell preparations. Recommended storage is at -20 °C with the antibody divided into single-use aliquots to limit repeated freeze-thaw exposure and preserve binding activity. Research examining chemoresistance phenotypes and comparing apoptotic signatures across normal versus malignant tissue contexts relies on this antibody to define how BCL2L10 contributes to cell survival decisions in cancer models.